Caution: Use an occlusive dressing or barrier cream if applying near the face, eyes, nipples, perineum, or any broken skin.Discontinue use if the patient develops significant skin irritation or chemical burns. Caution: Use gloves to apply and wash hands thoroughly after application.Apply capsaicin cream (0.075%) topically to the abdomen and/or back of arms up to three times daily (may cause initial discomfort).Based on the increasing amount of supporting literature and low risk associated with its use, capsaicin can be considered as first-line treatment in cases of clear diagnosis or with recurrent presentations. Capsaicin cream Cannabinoid hyperemesis syndrome ( CHS ) is recurrent nausea, vomiting, and cramping abdominal pain that can occur due to prolonged, high-dose cannabis use. A new ED study from Colorado found that, while ED LOS was not impacted with capsaicin use, there were less total medications administered and a decrease in opioid requirements to treat the pain ( Wagner 2019). While the published data so far are of low methodological quality, they do support a favorable risk-benefit profile as an adjunctive treatment option ( McConachie 2019). Traditional therapies that may be effective include: hot showers, IV fluids, benzodiazepines, haloperidol or droperidol ( Lee 2019), and sometimes antiemetics.Ĭapsaicin cream is a great adjunctive therapy (yes, the over-the-counter product). Data Sources: A literature search using keywords related to cannabinoids, emesis, and capsaicin was performed in. The objective of this study is to systematically review the efficacy data for capsaicin in CHS. If you haven’t seen a case of this yet, you probably will soon with the increased availability of marijuana in the United States.įor a full review of CHS diagnosis, pathophysiology, and treatment, take a look at these two open-access articles ( Sorensen 2017, Lapoint 2018). Capsaicin is recommended as a reasonable first-line treatment approach for CHS despite limited clinical evidence regarding its use. Today’s pearl focuses on capsaicin in the treatment of Cannabinoid Hyperemesis Syndrome (CHS). An easy and topical option for patients with symptoms refractory to normal therapies If you notice any other effects, check with your healthcare professional. Abnormal skin odor change in or loss of taste Other side effects not listed may also occur in some patients. Today’s pearl is a nontraditional treatment for nausea/vomiting in patients with Cannabinoid Hyperemesis Syndrome. Case series of 5 patients with chronic cannabis use diagnosed with CHS and treated successfully with 0.075 capsaicin cream 8 Case report of 1 patient with CHS, treatment failed with metoclopramide and granisetron, but had successful treatment with 0.075 capsaicin cream 9 Case report of 1 patient with CHS, no relief of symptoms with zofran. nausea pain or tenderness around the eyes and cheekbones vomiting Incidence not known - patch only.
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